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The definitive treatment for endometriosis ends a woman's potential for pregnancy by removal of the uterus, tubes, and ovaries.

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The following reactions have been reported, a causal relationship to the administration of DANOCRINE has neither been confirmed nor refuted; allergic: urticaria, pruritus and rarely, nasal congestion; CNS effects: headache, nervousness and emotional lability, dizziness and fainting, depression, fatigue, sleep disorders, tremor, paresthesias, weakness, visual disturbances, and rarely, benign intracranial hypertension, anxiety, changes in appetite, chills, and rarely convulsions, Guillain-Barre syndrome; gastrointestinal: gastroenteritis, nausea, vomiting, constipation, and rarely, pancreatitis and splenic peliosis; musculoskeletal: muscle cramps or spasms, or pains, joint pain, joint lockup, joint swelling, pain in back, neck, or extremities, and rarely, carpal tunnel syndrome which may be secondary to fluid retention; genitourinary: hematuria, prolonged posttherapy amenorrhea; hematologic: an increase in red cell and platelet count.

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The major progestogenic agents used are Duphaston (Dydrogesterone), Provera (Medroxyprogesterone) and Primolut-N (Norethisterone).

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Talwin Nx (pentazocine and naloxone hydrochloride) analgesic; Carpuject line of injectables in pre-filled syringes; Plaquenil (hydroxychloroquine) for rheumatoid arthritis and lupus erythematosus; and Danocrine (danazol) for endometriosis.

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